Monday, August 28, 2006

Four-drug strategy reduces repeat miscarriages

Thu Jul 27, 2006 9:39 PM BST164

NEW YORK (Reuters Health) - For women who experience repeated unexplained miscarriages, the combination of prednisone, aspirin, folate, and progesterone increases their chances of having baby, a team of clinicians from Austria reports in the journal Fertility and Sterility.

Repeat or "recurrent" miscarriage is defined as at least three consecutive spontaneous pregnancy losses before 20 weeks of gestation. While higher maternal age, smoking, drinking, and other factors can raise the risk of miscarriage, oftentimes the cause is unknown.

Prednisone, aspirin, and progesterone have been reported to be effective in reducing recurrent unexplained miscarriage, Dr. Clemens B. Tempfer and colleagues at the University of Vienna School of Medicine point out, but combinations of these treatments have not been evaluated in clinical trials.

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